Property style
This 3-star hotel in SAINT LOUIS, MO, UNITED STATES offers accommodations suited for a variety of travel needs.
Hotel details & availability
Hampton Inn & Suites St. Louis/South I-55
SAINT LOUIS, MO, UNITED STATES
Current availability and rates for Hampton Inn & Suites St. Louis/South I-55
Search your travel dates to check current availability, room options and live rates for Hampton Inn & Suites St. Louis/South I-55 in SAINT LOUIS, MO.
Hotel overview
About Hampton Inn & Suites St. Louis/South I-55
A quick planning snapshot for Hampton Inn & Suites St. Louis/South I-55 in SAINT LOUIS, MO, UNITED STATES.
Hampton Inn & Suites St. Louis/South I-55 is a hotel located in SAINT LOUIS, MO, UNITED STATES. This hotel provides a practical and cost-effective option for travelers.
old world charm meets Midwest hospitality...welcome to the Hampton Inn and Suites-St. Louis South I-55 hotel.When you book the Hampton Inn and Suites St Louis/South I-55 hotel, you'll soon understand why the hotel is ranked #1 of all hotels in St. Louis based on TripAdvisor reviews! You'll love the mix of Old World charm and Midwest hospitality that characterizes the vibrant city of St. Louis. From the moment you're greeted by its signature Gateway Arch, you'll be glad you booked a stay at our Hampton Inn and Suites® St. Louis/South I-55 hotel near St. Louis downtown. After you check in, it will be hard to decide what to do first. Experience views from atop the Gateway Arch? Explore fabulous museums? Visit the St. Louis Zoo? We're close to the best that the city has to offer.View our St. Louis hotel packages and specialsEnjoy your extended stay in St. Louis with our beautiful hotel suites Explore historic Union Station or catch a game at Busch Stadium, home of the St. Louis Cardinals. The former industrial area of Laclede's Landing is now a bustling entertainment district that features live music, ranging from pop to jazz, dining and more.The Soulard neighborhood boasts jazz and bl
Best for
Hampton Inn & Suites St. Louis/South I-55 in SAINT LOUIS, MO, UNITED STATES can be suitable for couples, families, groups and business travelers, depending on the room type and services you choose.
Booking tip
When checking availability at Hampton Inn & Suites St. Louis/South I-55, pay attention to the room type, board plan (such as breakfast or all inclusive) and the cancellation policy to find the option that best matches your trip. The hotel is located in SAINT LOUIS, MO, which offers local dining, shopping and entertainment options for visitors. Travelers visiting UNITED STATES should verify entry requirements, passport validity and any travel advisories before booking.
Destination base
Stay in SAINT LOUIS, MO, UNITED STATES with access to local attractions, dining and transportation options.
Compare before booking
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Location
SAINT LOUIS, MO
Category
3 stars
Check-in
2026-09-08
Check-out
2026-09-15
Things to do near Hampton Inn & Suites St. Louis/South I-55
Nearby guideExplore places near Hampton Inn & Suites St. Louis/South I-55 in SAINT LOUIS, MO. The area may include attractions, museums, restaurants, nightlife and transportation options depending on what is available nearby.
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Good to know before booking
Room features, services, facilities, fees and included amenities can vary by selected room type,
rate, destination rules and property policy. Review the available option details before checkout.
Room details vary
Room features, services and facilities can change by selected room type and rate.
Local fees may apply
Taxes, resort fees or destination fees may apply depending on local rules and property policy.
Some extras cost more
Parking, spa access, premium drinks or transfers may require an extra charge.
Frequently asked questions about Hampton Inn & Suites St. Louis/South I-55
Quick answers about availability, location and trip fit before you continue to room options.
How can I check availability for Hampton Inn & Suites St. Louis/South I-55?
Use the availability button on this page to search your dates, room options and current rates.
Where is Hampton Inn & Suites St. Louis/South I-55 located?
Hampton Inn & Suites St. Louis/South I-55 is located in SAINT LOUIS, MO, UNITED STATES. The listed address is 4200 MIDAMERICA LANE.
Is Hampton Inn & Suites St. Louis/South I-55 suitable for families or couples?
Many hotels in SAINT LOUIS, MO welcome different types of travelers. Exact services for families, couples or business travelers depend on the property and the selected room type.
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